How Does INCIVEK Triple Therapy Work?
INCIVEK Triple Therapy is a combination of 3 prescription medicines (INCIVEK +
peginterferon alfa + ribavirin) used to treat chronic hepatitis C (genotype 1)
infection in adults with stable liver problems, who have not been treated before or who have failed previous treatment.
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How does INCIVEK Triple Therapy work?
Each of the 3 medicines in INCIVEK Triple Therapy has a specific job:
- Hepatitis C is a virus that makes copies
of itself inside the body
- INCIVEK directly targets the hepatitis C
virus as it multiplies
- These medicines are used to help your body clear the remaining virus
- Peginterferon alfa works with the body’s immune system to ramp up its defenses and stop the virus from making copies of itself
INCIVEK Triple Therapy from start to finish
Day 1: Start all 3 medicines together: INCIVEK, peginterferon alfa, and ribavirin.
Your healthcare provider will decide if you stop treatment at week 24 or 48, based on your blood test results, your treatment history, and your liver health.
While INCIVEK Triple Therapy lasts 24 or 48 weeks, you will stop taking INCIVEK after 12 weeks.
Viral lab tests during treatment
Certain lab tests, along with your treatment history and liver health, help your healthcare provider understand how and if your body is responding to treatment and help them decide how long your treatment will be.
- The INCIVEK part of your treatment is finished at week 12
- If the virus is undetectable at weeks 4 and 12, your healthcare provider will tell you to continue peginterferon alfa and ribavirin for another 12 or 36 weeks, depending on your treatment history and liver health
- If the virus is detectable at weeks 4 or 12 but low enough to show that the treatment is working, your healthcare provider may have you continue peginterferon alfa and ribavirin for a total of 48 weeks
2. Talk with your healthcare provider about any other tests you may need during treatment, or if you have any questions about the length of your treatment. Your healthcare provider will also periodically test you for anemia (low red blood cell count) and other side effects in order to help manage your treatment.
3. Six months after you finish treatment, you will have another blood test. If that test shows the virus is undetectable, you are cured. This is also known as Sustained Virologic Response (SVR).